Fig. 5

Survival cures of 127 oral squamous cell carcinoma patients. a Overall survival (OS) curves of 127 oral squamous cell carcinoma patients. In OSCC patients, the expression of CD68-positive macrophages and CD163-positive macrophages in tumor nest, CD163 in tumor cells, vimentin both in tumor and at the tumor invasion front was associated with poor OS (b, d, g, j, k). The expression of CD68-positive macrophages and CD163-positive macrophages in tumor stroma, CD68 in tumor cells, E-cadherin both in tumor and at the tumor invasion front was not associated with poor OS (c, e, f, h, i). L, low (≤ 6/ high-power field); H, high (≥ 8/ high-power field); N, negative; L, low expression; H, high expression. CD68+ 1: CD68-positive macrophages counts in tumor nest; CD68+ 2: CD68-positive macrophages counts in tumor stroma; CD163+ 1: CD163-positive macrophages counts in tumor nest; CD163+ 2: CD163-positive macrophages counts in tumor stroma; CD68: CD68 expression in tumors; CD163: CD163 expression in tumors; E-cad 1: E-cadherin expression in tumor; E-cad 2: E-cadherin expression at the invasive front of tumor; vim 1: vimentin expression in tumor; vim 2: vimentin expression at the invasive front of tumor