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Table 1 Correlation between clinical parameters and CD68+ macrophages counts in tumor nest and tumor stroma

From: Tumor-associated macrophages correlate with the clinicopathological features and poor outcomes via inducing epithelial to mesenchymal transition in oral squamous cell carcinoma

Variable No. CD68+ macrophages counts in tumor nest CD68+ macrophages counts in tumor stroma
Low(≤6/HPF) High(>6/HPF) P Low(≤8/HPF) High(>8/HPF) P
Sex     0.176    0.060
 Male 74 34 40   30 44  
 Female 53 18 35   13 40  
Age (years)     0.773    0.927
 ≤50 26 10 16   9 17  
 >50 101 42 59   34 67  
Tumor location     0.034    0.346
 Tongue 52 29 23   20 32  
 Gingiva 26 7 19   8 18  
 Buccal mucosa 31 8 23   6 25  
 Lip 4 3 1   2 2  
 Floor of the mouth 2 1 1   1 1  
 Others 12 4 8   6 6  
Tumor size     0.665    0.369
 T1 21 9 12   7 14  
 T2 68 28 40   21 47  
 T3 26 12 14   8 18  
 T4 12 3 9   7 5  
Lymph node metastasis     0.850    0.321
 N0 72 30 42   27 45  
 N (+) 55 22 33   16 39  
Metastasis     0.793    0.627
 M0 125 51 74   42 83  
 M (+) 2 1 1   1 1  
Clinical stage     0.262    0.699
 I 12 5 7   4 8  
 II 42 19 23   17 25  
 III 34 16 18   8 26  
 IV 39 12 27   14 25  
Pathological grade     0.135    0.296
 I 76 34 42   24 52  
 II 42 18 24   13 29  
 III 9 0 9   6 3  
Recurrence     0.111    0.259
 No 83 39 44   25 58  
 Yes 42 13 29   18 24  
 Lost 2 0 2   0 2  
Follow-up     0.005    0.218
 Live 91 45 46   27 64  
 Dead 33 7 26   15 18  
 Lost 3 0 3   1 2  
  1. No., number of patients; HPF, high-power field. N0, no lymph node metastasis; N (+), node metastasis. M0, no metastasis; M(+), metastasis
  2. Bold values signify P < 0.05