|
Variable
|
No.
|
CD68+ macrophages counts in tumor nest
|
CD68+ macrophages counts in tumor stroma
|
|---|
|
Low(≤6/HPF)
|
High(>6/HPF)
|
P
|
Low(≤8/HPF)
|
High(>8/HPF)
|
P
|
|---|
|
Sex
| | | |
0.176
| | |
0.060
|
|
Male
|
74
|
34
|
40
| |
30
|
44
| |
|
Female
|
53
|
18
|
35
| |
13
|
40
| |
|
Age (years)
| | | |
0.773
| | |
0.927
|
|
≤50
|
26
|
10
|
16
| |
9
|
17
| |
|
>50
|
101
|
42
|
59
| |
34
|
67
| |
|
Tumor location
| | | |
0.034
| | |
0.346
|
|
Tongue
|
52
|
29
|
23
| |
20
|
32
| |
|
Gingiva
|
26
|
7
|
19
| |
8
|
18
| |
|
Buccal mucosa
|
31
|
8
|
23
| |
6
|
25
| |
|
Lip
|
4
|
3
|
1
| |
2
|
2
| |
|
Floor of the mouth
|
2
|
1
|
1
| |
1
|
1
| |
|
Others
|
12
|
4
|
8
| |
6
|
6
| |
|
Tumor size
| | | |
0.665
| | |
0.369
|
|
T1
|
21
|
9
|
12
| |
7
|
14
| |
|
T2
|
68
|
28
|
40
| |
21
|
47
| |
|
T3
|
26
|
12
|
14
| |
8
|
18
| |
|
T4
|
12
|
3
|
9
| |
7
|
5
| |
|
Lymph node metastasis
| | | |
0.850
| | |
0.321
|
|
N0
|
72
|
30
|
42
| |
27
|
45
| |
|
N (+)
|
55
|
22
|
33
| |
16
|
39
| |
|
Metastasis
| | | |
0.793
| | |
0.627
|
|
M0
|
125
|
51
|
74
| |
42
|
83
| |
|
M (+)
|
2
|
1
|
1
| |
1
|
1
| |
|
Clinical stage
| | | |
0.262
| | |
0.699
|
|
I
|
12
|
5
|
7
| |
4
|
8
| |
|
II
|
42
|
19
|
23
| |
17
|
25
| |
|
III
|
34
|
16
|
18
| |
8
|
26
| |
|
IV
|
39
|
12
|
27
| |
14
|
25
| |
|
Pathological grade
| | | |
0.135
| | |
0.296
|
|
I
|
76
|
34
|
42
| |
24
|
52
| |
|
II
|
42
|
18
|
24
| |
13
|
29
| |
|
III
|
9
|
0
|
9
| |
6
|
3
| |
|
Recurrence
| | | |
0.111
| | |
0.259
|
|
No
|
83
|
39
|
44
| |
25
|
58
| |
|
Yes
|
42
|
13
|
29
| |
18
|
24
| |
|
Lost
|
2
|
0
|
2
| |
0
|
2
| |
|
Follow-up
| | | |
0.005
| | |
0.218
|
|
Live
|
91
|
45
|
46
| |
27
|
64
| |
|
Dead
|
33
|
7
|
26
| |
15
|
18
| |
|
Lost
|
3
|
0
|
3
| |
1
|
2
| |
- No., number of patients; HPF, high-power field. N0, no lymph node metastasis; N (+), node metastasis. M0, no metastasis; M(+), metastasis
- Bold values signify P < 0.05
