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Table 2 Correlation between clinical parameters and CD163+ macrophages counts in tumor nest and tumor stroma

From: Tumor-associated macrophages correlate with the clinicopathological features and poor outcomes via inducing epithelial to mesenchymal transition in oral squamous cell carcinoma

Variable No. CD163+ macrophages counts in tumor nest CD163+ macrophages counts in tumor stroma
Low(≤6/HPF) High(>6/HPF) P Low(≤8/HPF) High(>8/HPF) P
Sex     0.037    0.846
 Male 74 36 38   32 42  
 Female 53 16 37   22 31  
Age (years)     0.874    0.674
 ≤50 26 11 15   12 14  
 >50 101 41 60   42 59  
Tumor location     0.389    0.057
 Tongue 52 24 28   22 30  
 Gingiva 26 9 17   17 9  
 Buccal mucosa 31 9 22   7 24  
 Lip 4 3 1   2 2  
 Floor of the mouth 2 1 1   1 1  
 Others 12 6 6   5 7  
Tumor size     0.921    0.335
 T1 21 7 14   7 14  
 T2 68 31 37   30 38  
 T3 26 8 18   9 17  
 T4 12 6 6   8 4  
Lymph node metastasis     0.200    0.889
 N0 72 33 39   31 41  
 N (+) 55 19 36   23 32  
Metastasis     0.235    0.829
 M0 125 52 73   53 72  
 M (+) 2 0 2   1 1  
Clinical stage     0.059    0.725
 I 12 5 7   4 8  
 II 42 21 21   21 21  
 III 34 16 18   13 21  
 IV 39 10 29   16 23  
Pathological grade     0.211    0.469
 I 76 35 41   35 41  
 II 42 13 29   14 28  
 III 9 4 5   5 4  
Recurrence     0.22    0.01
 No 83 38 45   28 55  
 Yes 42 13 29   24 18  
 Lost 2 1 1   2 0  
Follow-up     0.04    0.040
 Live 91 43 48   34 57  
 Dead 33 8 25   17 16  
 Lost 3 1 2   3 0  
  1. No., number of patients; HPF, high-power field. N0, no lymph node metastasis; N (+), node metastasis. M0, no metastasis; M(+), metastasis
  2. Bold values signify P < 0.05