Fig. 1

Differentially expressed miRNAs after MLL-AF9 knockdown in THP1 cells. TaqMan low density array analysis was utilized for quantification of differential expression which is shown relative to non-targeting control siRNA treatments. Bars indicate standard error of the mean. Columns on the right show log₂ fold change (log₂FC) and p-value of the corresponding miRNA. For miRNAs which were turned “on” or “off”, i.e. not detectable in either both control or both MLL-AF9 knockdown treatments, a lower limit of differential expression is reported as described in methods. Here no p-value can be calculated. n.c., not calculable