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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Atorvastatin (Lipitor) attenuates the effects of aspirin on pancreatic cancerogenesis and the chemotherapeutic efficacy of gemcitabine on pancreatic cancer by promoting M2 polarized tumor associated macrophages

Fig. 2

Aspirin inhibited pancreatic cancer-induced MDSC and M2 in vitro, however Lipitor promoted pancreatic cancer-induced M2. a The FCM results indicated that aspirin significantly inhibited pancreatic cancer-induced MDSC, however Lipitor did not obviously affect pancreatic cancer-induced MDSC. b The representative plots of FCM. c Western blotting of arginase-1 confirmed the results of FCM. d The FCM results indicated that aspirin significantly inhibited pancreatic cancer-induced M2, on the contrary, Lipitor obviously promoted pancreatic cancer-induced M2. e The representative plots of FCM. f Western blotting of CD206 onfirmed the results of FCM. Each experiment was performed in triplicats and the representative one was shown. ANOVA analysis, SNK-q test, * P < 0.05, ** P < 0.01

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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