Fig. 3

Angiogenesis assay. HUVEC tube-forming assay measured by the number of junctions: a, untreated HUVEC; b, vehicle treated HUVEC; c, HUVEC treated with 40 μM AqB013; d, HUVEC treated with 80 μM AqB013 (40 x magnification, scale bar = 0.5 mm); e, graph shows significant inhibition of endothelial tube formation by AqB013 at 40 μM and 80 μM, **p <0.01, ****p < 0.0001 respectively (ANOVA). f, AqB013 treatment had no effect on proliferation of HUVECs