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Table 1 Patients’ characteristics

From: Subpopulation Treatment Effect Pattern Plot (STEPP) analysis of Ki67 assay according to histology: prognostic relevance for resected early stage ‘pure’ and ‘mixed’ lobular breast cancer

Category Patients number (%)
Menopausal status  
 Premenopausal 115 (28.4)
 Postmenopausal 290 (71.6)
Performance status (ECOG)  
 0 379 (93.6)
 1 22 (5.4)
 2 4 (1.0)
Type of surgery  
 Tumorectomy 173 (42.7)
 Quadrantectomy 83 (20.5)
 Mastectomy 149 (36.8)
Sentinel lymph-node biopsy  
 No 157 (38.8)
 Yes 248 (61.2)
Histological subtype  
 Pure lobular 290 (71.6)
 Ductal-lobular 105 (25.9)
 Others 10 (2.5)
T descriptor according to TNM [7° Edition]  
 1 233 (57.5)
 2 128 (31.6)
 3 31 (7.7)
 4 11 (2.7)
Lymph-node status  
 Negative 234 (57.8)
 Positive 155 (38.2)
 Unknown 16 (4.0)
Estrogen receptor status  
 Negative 12 (3.0)
 Positive 379 (93.6)
 Unknown 14 (3.4)
Progesterone receptor status  
 Negative 40 (9.9)
 Positive 335 (82.7)
 Unknown 30 (7.4)
HER2 status  
 Negative 259 (64.0)
 Positive 20 (4.9)
 Unknown 126 (31.1)
Histological grade  
 1 67 (16.5)
 2 155 (38.3)
 3 56 (13.8)
 Unknown 127 (31.4)
Vascular invasion  
 Absent 211 (52.1)
 Present 84 (20.7)
 Unknown 110 (27.2)
Multifocality  
 Absent 316 (78.0)
 Present 83 (20.5)
 Unknown 6 (1.5)
Adjuvant hormonotherapy  
 No 59 (14.6)
 Yes 346 (85.4)
Adjuvant chemotherapy  
 No 245 (60.5)
 Yes 160 (39.5)
Adjuvant radiotherapy  
 No 132 (32.6)
 Yes 259 (64.0)
 Unknown 14 (3.4)
  1. Legend – Table 1: ECOG Eastern Cooperative Oncology Group