Fig. 4

Coagulation and fibrin formation and inhibition assays. a Coagulation times of platelets and microparticles (MPs) from healthy subjects (n = 33), stage I (n = 16), II (n = 47), III (n = 28), or IV (n = 21) colon cancer patients were measured. b Coagulation time of platelets and MPs in 21 stage IV colon cancer patients was detected in the absence or presence of lactadherin (128 mM) or anti-TF (25.6 μg/ml). Fibrin production on c platelets or d MPs was detected in the presence of recalcified MDP with or without 128 nM lactadherin or 25.6 μg/ml anti-TF. Data displayed are mean ± SD. *P <0.05