Table 1 Baseline characteristics of patients with colon cancer and healthy subjects at inclusion

Gender (Male, %)

17 (51.52 %)

6 (37.50 %)

29 (61.70 %)

12 (42.86 %)

8 (38.10 %)

Age (years)

60.72 ± 10.26

61.38 ± 11.71

63.51 ± 10.50

64.38 ± 9.99

58.86 ± 12.00

Albumin (g/l)

38.91 ± 4.87

33.96 ± 6.71

36.22 ± 6.22

36.99 ± 6.25

36.97 ± 4.62

Total cholesterol (mM)

3.96 ± 0.62

3.93 ± 1.14

3.85 ± 1.24

3.50 ± 0.89

3.48 ± 1.17

Triglycerides (mM)

0.94 ± 0.46

1.26 ± 0.35

1.37 ± 0.80

1.31 ± 0.66

1.67 ± 0.61

CEA (ng/ml)

ND

2.13 (1.08-2.30)

4.73 (3.23-18.88)^b

3.16 (2.55-7.18)^b

10.54 (8.91-13.64)^bcd

CA199 (U/ml)

ND

9.45 (5.38-10.19)

15.76 (10.73-34.51)^b

19.43 (10.67-46.56)^b

64.07 (2.56-779.92)^bcd

Platelet count (10⁹/L)

248.35 ± 50.32

281.40 ± 94.95

259.62 ± 91.42

273.79 ± 87.21

309.97 ± 77.95

Erythrocyte count (10¹²/L)

4.35 ± 0.42

4.16 ± 0.71

4.43 ± 0.83

4.50 ± 0.59

4.23 ± 0.84

Hemoglobin (g/L)

126.49 ± 20.37

117.51 ± 32.60

123.81 ± 30.15

124.73 ± 27.60

120.23 ± 29.76

PT (s)

11.70 ± 0.72

10.83 ± 0.70

11.86 ± 0.92

11.26 ± 0.87

11.06 ± 0.81

APTT (s)

31.41 ± 2.85

27.14 ± 3.41^a

27.84 ± 4.01^a

25.39 ± 2.85^abc

24.81 ± 2.56^abc

D-dimer (mg/L)

0.13 (0.06-0.18)

0.31 (0.19-1.07)^a

0.38 (0.22-1.78)^a

0.72 (0.32-1.16)^abc

0.73 (0.29-1.12)^abc

Fibrinogen (g/L)

3.47 ± 1.03

3.59 ± 1.66

3.89 ± 1.19

3.42 ± 0.72

3.81 ± 0.58

Current smoking, n (%)

5 (15.15 %)

2 (12.50 %)

9 (19.15 %)

6 (21.43 %)

5 (23.81 %)

Thrombotic events, n (%)

2 (6.06 %)

3 (18.75 %)^a

10 (21.28 %)^a

9 (32.14 %)^a

6 (28.57 %)^a