Fig. 1

PPP2R2D is down-regulated in HCC. a PPP2R2D expression levels in two cohorts of HCC patients [14, 15]. The mRNA microarray data were obtained from GEO database (Accession No.: GSE59259 and GSE6764, *P < 0.05). b Kaplan-Meier analysis showing overall survival of HCC patients [16] with two different levels of PPP2R2D expression (Accession No.: GSE54236, PPP2R2D expression was treated as a binary variable divided into high or low expression according to the median, Log-rank, *P < 0.05). c PPP2R2D mRNA and (d) B55δ protein levels were evaluated in normal hepatic cell lines and HCC cell lines. The data shown in the bar graph are the mean ± SD of three independent experiments. *P < 0.01 as compared with L02 cells; ^# P < 0.01 as compared with QSG7701 cells