Table 2 The Cox proportional hazard regression analyses for overall survival

Gender

 Male

14

1

 Female

84

0.820(0.390-1.727)

0.602

n.a.

Age (years)

 >60

27

1

 ≤60

71

0.815(0.456-1.456)

0.490

n.a.

Hepatitis B status

 Negative

17

1

 Positive

81

0.982(0.496-1.942)

0.958

n.a.

AFP(ng/ml)

 ≥20

70

1

 <20

28

0.941(0.549-1.612)

0.824

n.a.

Liver cirrhosis

 Absent

17

1

 Present

81

0.606(0.329-1.118)

0.109

n.a.

Tumor size (cm)

 ≤3

36

1

1

 > 3

62

2.998(1.714-5.244)

<0.001

0.901(0.543-1.496)

0.687

Number of tumors

 Single

47

1

1

 Multiple (≥ 2)

51

2.772(1.632-4.707)

<0.001

1.004(0.479-2.106)

0.991

Vascular invasion

 Absent

45

1

1

 Present

53

2.631(1.570-4.410)

<0.001

1.758(1.313-2.353)

<0.001

Child-Pugh classification

 A

76

1

 B

22

0.862(0.459-1.617)

0.643

n.a.

Edmondson-Steiner grade

 I-II

72

1

 III-IV

26

0.984(0.573-1.688)

0.952

n.a.

TNM stage

 I/ II

49

1

1

 III

49

2.003(1.490-2.692)

<0.001

0.861(0.507-1.463)

0.580

BCLC

 0-A

54

1

1

 B/C

44

1.818(1.381-2.394)

<0.001

2.118(1.177-3.814)

0.012

SYNJ2BP expression

 Low

39

1

1

 High

59

0.216(0.122-0.384)

<0.001

0.279(0.125-0.620)

0.002