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Fig. 4 | Journal of Experimental & Clinical Cancer Research

Fig. 4

From: Evaluation of intraarterial and intravenous cisplatin chemotherapy in the treatment of metastatic osteosarcoma using an orthotopic xenograft mouse model

Fig. 4

Histological evaluation of tumor necrosis. a Representative examples of necrotic (black dashed lines) tumor areas are shown for each treatment group. Areas overlaid with a striped pattern were not considered for evaluation (e.g. bone, muscle, absence of tissue). Scale bar corresponds to 500 μm (5X). b Quantitation of tumor necrosis, normalized to the total tumor area which was available for analysis. *p < 0.05 as compared to the indicated treatment

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