A restricted signature of serum miRNAs distinguishes glioblastoma from lower grade gliomas

Regazzo, Giulia; Terrenato, Irene; Spagnuolo, Manuela; Carosi, Mariantonia; Cognetti, Gaetana; Cicchillitti, Lucia; Sperati, Francesca; Villani, Veronica; Carapella, Carmine; Piaggio, Giulia; Pelosi, Andrea; Rizzo, Maria Giulia

doi:10.1186/s13046-016-0393-0

Journal of Experimental & Clinical Cancer Research

Table 2 Studies included in the systematic review

From: A restricted signature of serum miRNAs distinguishes glioblastoma from lower grade gliomas

MicroRNA	Cancer type	Biofluid type	Deregulation	Author	Reference
miR-125b	Bladder cancer	Urine	↓ tumors vs controls	Zhang et al.	46
	Bladder cancer	Urine	↓ high-grades vs low-grades	Zhang et al.	46
	Uveal Melanoma	Plasma	↑tumors vs controls	Achberger et al.	47
	Advanced Melanoma	Serum^a	↓tumors vs controls	Alegre et al.	48
	Ewing’s sarcoma	Serum	↓ tumors vs controls	Nie et al.	49
	Breast cancer	Serum	↑ late stages vs controls	Wang et al.	50
	Breast cancer	Serum	↑ late stages vs early stages	Wang et al.	50
	Breast cancer	Urine	↓ tumors vs controls	Erbes et al.	51
	Breast cancer	Serum	↑ tumors vs controls	Mar-Aguilar et al.	52
	Breast cancer	Serum	↑ tumors vs controls	Matamala et al.	53
	Non-small-cell lung cancer	Serum	↑ tumorsvs controls	Yuxia et al.	54
	Non-small-cell lung cancer	Serum	↑ late stages vs early stages	Yuxia et al.	54
	Non-small-cell lung cancer	Plasma	↑ tumors vs controls	Zhao et al.	55
	Non-small-cell lung cancer	Plasma	↑ late stages vs early stages	Zhao et al.	55
	Diffuse large B-cell lymphoma	Serum	↑ tumors vs controls	Yuan et al.	56
	Laryngeal squamous cell carcinoma	Plasma	↓ tumors vs controls	Ayaz et al.	57
	Glioma	Serum	↓ tumors vs controls	Wei et al.	32
	Glioma	Serum	↓ high-grades vs low-grades	Wei et al.	32
	Colorectal neoplasia	Serum	↑ tumors vs controls	Yamada et al.	58
miR-497	Bladder cancer	Plasma	↓ tumors vs controls	Du et al.	59
	Astrocytoma	Serum	↓ tumors vs controls	Yang et al.	26
	Nasopharyngeal carcinoma	Plasma	↓ tumors vs controls	Wang et al.	60
	Prostate cancer	Serum	↓ tumors vs controls	Kong et al.	61
	Cervical cancer	Serum	↑ tumors vs controls	Zhang et al.	62

^aExosomal fraction only

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ISSN: 1756-9966

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