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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Activation of the JNK-c-Jun pathway in response to irradiation facilitates Fas ligand secretion in hepatoma cells and increases hepatocyte injury

Fig. 2

Irradiation altered the expressions of some proliferation and apoptosis- associated cytokines in SMMC7721 cells. a 24 h after irradiation, expressions of nine proliferation- and apoptosis- associated cytokines were examined using RT-PCR.*P < 0.05, **P < 0.01, ***P < 0.001. b Effect of radiation on FasL expression in human hepatoma cells with different malignant potentials was explored. Five types of hepatoma cells indicated were treated with single doses of 0-8Gy respectively, and incubated for 24 h. The expressions of FasL in five hepatoma cells were measured by RT-PCR. c SMMC7721 cells and MHCC97H cells, representing low and high malignant potential, as indicated, were treated with single doses of 0–8Gy, and incubated for 12, 24, and 48 h respectively, then the concentration of the secreted FasL in culture medium was measured by ELISA

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