Table 2 Relations between HER3 and heregulin-1ß mRNA fold inductions (T/NT) and the pathological characteristics of 85 HCC

 Yes

 No

27

58

2.38 [0.29–20.25]

1.55 [0.07–15.51]

0.033

0.02 [0.00–4.56]

0.13 [0.00–25.46]

0.075

 Yes

 No

21

64

1.30 [0.25–12.86]

2.21 [0.07–20.25]

0.016

0.06 [0.00–4.17]

0.095 [0.00–25.46]

0.724

 Yes

 No

11

74

2.74 [0.69– 5.30]

1.60 [0.07–20.25]

0.313

0.33 [0.02–2.04]

0.05 [0.00–25.46]

0.074

 Yes

 No

8

77

1.32 [0.85–4.50]

2.06 [0.07–20.25]

0.425

0.715 [0.05–25.46]

0.06 [0.00–4.56]

0.011

 Yes

 No

5

80

2.11 [0.96–6.77]

1.85 [0.07–20.25]

0.727

0.10 [0.00–0.89]

0.08 [0.00–25.46]

0.783

 Yes

 No

50

35

1.52 [0.25–20.25]

2.60 [0.07–15.51]

0.150

0.090 [0.00–4.17]

0.090 [0.00–25.46]

0.719

  < 400 ng/ml

  ≥ 400 ng/ml

47

34

1.85 [0.07–20.25]

2.09 [0.25–15.51]

0.867

0.13 [0.00–4.56]

0.05 [0.00–25.46]

0.293

  < 5 cm

  ≥ 5 cm

44

41

1.47 [0.25–7.89]

2.68 [0.07–20.25]

0.019

0.09 [0.00–4.56]

0.09 [0.00–25.46]

0.631

 Yes

 No

18

67

2.05 [0.32–20.25]

1.94 [0.07–7.89]

0.796

0.24 [0.00–4.17]

0.06 [0.00–25.46]

0.310

 Yes

 No

26

59

2.11 [0.07–20.25]

1.58 [0.25–7.89]

0.458

0.15 [0.00–25.46]

0.05 [0.00–4.56]

0.164

 Well/moderate

 Poor

61

24

2.22 [0.29–20.25]

1.43 [0.07–6.77]

0.021

0.23 [0.00–25.46]

0.01 [0.00–1.76]

0.001

  < 5 %

  ≥ 5 %

65

17

1.85 [0.25–20.25]

2.44 [0.07–15.51]

0.926

0.11 [0.00–25.46]

0.01 [0.00–1.06]

0.006

 Yes

 No

41

44

2.08 [0.07–20.25]

1.56 [0.29–6.94]

0.194

0.08 [0.00–25.46]

0.09 [0.00–4.56]

0.624