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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: MiR-137 and miR-34a directly target Snail and inhibit EMT, invasion and sphere-forming ability of ovarian cancer cells

Fig. 1

MiR-137 and miR-34a are downregulated in OC tissues and decreased expressions of miR-137 and miR-34a are associated with poor survival in OC patients. a Venn diagram showing the overlap of miRNAs that were predicted to bind to the Snail 3′-UTR by alternative algorithms (TargetScan, miRSystem and DIANA-MicroT-CDS). The 6 predicted miRNAs were common to these three algorithms. b, c qPCR analysis of miR-137 (b) and miR-34a (c) levels in 50 paired cancerous and normal tissue samples from OC patients. d, e Kaplan-Meier analysis of overall survival in 50 OC patients with high median (n = 25) or low median (n = 25) expression levels of miR-137 (d) or miR-34a (e)

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