Fig. 1

miR-501-5p is upregulated in human gastric cancer tissues and cell lines. a miR-501-5p levels remained low in normal gastric tissues but became dramatically elevated in gastric cancer tissues by analyzing The Cancer Genome Atlas (TCGA) gastric cancer miRNA sequencing data sets (Normal, n = 41; gastric cancer, n = 395). P < 0.001, 2-tailed Student’s t-test. b and c Real-time PCR analysis of miR-501-5p expression in normal gastric epithelial cell (NGEC) and 5 cultured gastric cancer cell lines (b), and in 10 pairs of gastric cancer samples (T) and adjacent normal tissues (ANT) (c). Transcript levels were normalized by U6 expression. Error bars represent the mean ± s.d. of three independent experiments. *P < 0.05