From: Cell cycle checkpoint in cancer: a therapeutically targetable double-edged sword
Target | Drug | References | |
---|---|---|---|
S and G2/M checkpoint targeting drugs | |||
Chk1/2 | UCN-01 | ||
ICP-1 | [36] | ||
PF00477736 | |||
XL9844 | [43] | ||
PD321852 | [44] | ||
CEP3891 | [45] | ||
AZD7762 | [46] | ||
LY2603618 | [47] | ||
Gö6976 | [48] | ||
SCH900776 (MK-8776) | |||
CCT244747 | [51] | ||
ATR | NU6027 | [54] | |
Wee1 | MK-1775 | ||
Spindle assembly checkpoint targeting drugs | |||
Microtubular β-tubulin | Taxanes, Vinca alkaloids | ||
Wee1 | MK-1775 | [92] |