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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Hepatitis B virus X protein promotes interleukin-7 receptor expression via NF-κB and Notch1 pathway to facilitate proliferation and migration of hepatitis B virus-related hepatoma cells

Fig. 3

The effect of activated NF-κB and Notch 1 pathways on the expression of IL-7R mediated by HBX. a The expression of phosphorylated P65 and Notch1 in hepatoma cells stably transfected with HBX. b The selection of a suitable concentration of BAY11-7082 used to inhibit the activation of NF-κB pathway in hepatoma cells stably transfected with HBX. c The selection of a suitable concentration of GSI-953 used to inhibit Notch1 expression in hepatoma cells stably transfected with HBX. d and e The inhibitory effect of 10 μM BAY11-7082 and GSI-953 on the expression of IL-7R in hepatoma cells stably transfected with HBX. f and g The inhibitory effect of 10 μM BAY11-7082 on IL-7R expression in hepatoma cells transfected with HBV plasmids. h and i The inhibitory effect of 10 μM GSI-953 on IL-7R expression in hepatoma cells transfected with the HBV plasmid

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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