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Fig. 4 | Journal of Experimental & Clinical Cancer Research

Fig. 4

From: Hepatitis B virus X protein promotes interleukin-7 receptor expression via NF-κB and Notch1 pathway to facilitate proliferation and migration of hepatitis B virus-related hepatoma cells

Fig. 4

The role of IL-7R in intracellular pathways, molecules, and EMT in HBX-positive hepatoma cells. a IL-7R shRNA inhibition of IL-7R expression in hepatoma cells stably transfected with HBX. shNC cells, cells transfected with shRNA control vectors; shIL-7R cells, cells transfected with IL-7R shRNA vectors. b The role of IL-7R in the activation of JNK, AKT, and STAT5 in hepatoma cells stably transfected with HBX. HBX-shNC cells, HBX-positive cells transfected with shRNA plasmids. HBX-shIL-7R cells, HBX-positive cells transfected with IL-7R shRNA plasmid. c The function of IL-7R on CyclinD1 and MMP-9 in hepatoma cells stably transfected with HBX. d The role of IL-7R in the EMT of hepatoma cells steadily transfected with HBX

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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