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Table 1 The cytotoxicity of B5G9 in HepG2, HepG2/ADM, Hep3B and Bel-7402 hepatoma carcinoma cell lines

From: A piperazidine derivative of 23-hydroxy betulinic acid induces a mitochondria-derived ROS burst to trigger apoptotic cell death in hepatocellular carcinoma cells

Compounds

IC50 (μM) (24 h)

HepG2

HepG2/ADM

Hep3B

Bel-7402

B5G9

3.73 ± 0.25

9.94 ± 0.50

10.00 ± 0.55

13.80 ± 0.65

23-HBA

30.35 ± 2.76

40.67 ± 3.73

39.78 ± 3.56

42.78 ± 4.03

  1. HepG2, HepG2/ADM, Hep3B and Bel-7402 cells were treated with different concentrations of B5G9 and 23-HBA for 24 h. Cell viability was measured by MTT assay and IC50 values were calculated according to the MTT curves
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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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