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Table 3 Univariate and multivariate analysis of prognostic factors for overall survival

From: CCDC88A, a prognostic factor for human pancreatic cancers, promotes the motility and invasiveness of pancreatic cancer cells

 

Overall survival

Univariate

Multivariate

HR (95% CI)

P

HR (95% CI)

P

Stagea

0 + IA + IB

IIA

IIB

III + IV

1.0 (reference)

1.159 (0.714–1.881)

1.356 (0.854–2.151)

3.035 (1.301–7.081)

0.549

0.196

0.010

1.0 (reference)

5.705 (1.929–16.88)

6.270 (2.160–18.20)

11.10 (3.012–40.92)

1.650e–03

7.361e–04

2.985e–04

Age

1.025 (0.998–1.053)

0.067

1.024 (0.996–1.052)

0.086

Gender

1.249 (0.771–2.023)

0.366

1.236 (0.759–2.012)

0.393

CCDC88A expression

0.497 (0.295–0.836)

0.008

0.519 (0.306–0.877)

0.014

Diameter of primary tumor

1.338 (1.176–1.524)

1.045e–05

  

Histologyb

1.383 (0.846–2.261)

0.1965

  

Lymphatic invasionb

(ly0 + ly1 or ly2 + ly3)

1.269 (0.751–2.145)

0.3733

  

Venous invasionb

(v0 + v1 or v2 + v3)

1.928 (1.034–3.593)

0.0388

  

Intrapancreatic nerve invasionb (n0 + n1 or n2 + n3)

1.500 (0.947–2.377)

0.0839

  
  1. aClassified according to the classification of International Union against Cancer
  2. bClassified according to the classification of pancreatic cancer of Japan Pancreas Society