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Table 3 Univariate and multivariate analysis of prognostic factors for overall survival

From: CCDC88A, a prognostic factor for human pancreatic cancers, promotes the motility and invasiveness of pancreatic cancer cells

  Overall survival
Univariate Multivariate
HR (95% CI) P HR (95% CI) P
Stagea
0 + IA + IB
IIA
IIB
III + IV
1.0 (reference)
1.159 (0.714–1.881)
1.356 (0.854–2.151)
3.035 (1.301–7.081)
0.549
0.196
0.010
1.0 (reference)
5.705 (1.929–16.88)
6.270 (2.160–18.20)
11.10 (3.012–40.92)
1.650e–03
7.361e–04
2.985e–04
Age 1.025 (0.998–1.053) 0.067 1.024 (0.996–1.052) 0.086
Gender 1.249 (0.771–2.023) 0.366 1.236 (0.759–2.012) 0.393
CCDC88A expression 0.497 (0.295–0.836) 0.008 0.519 (0.306–0.877) 0.014
Diameter of primary tumor 1.338 (1.176–1.524) 1.045e–05   
Histologyb 1.383 (0.846–2.261) 0.1965   
Lymphatic invasionb
(ly0 + ly1 or ly2 + ly3)
1.269 (0.751–2.145) 0.3733   
Venous invasionb
(v0 + v1 or v2 + v3)
1.928 (1.034–3.593) 0.0388   
Intrapancreatic nerve invasionb (n0 + n1 or n2 + n3) 1.500 (0.947–2.377) 0.0839   
  1. aClassified according to the classification of International Union against Cancer
  2. bClassified according to the classification of pancreatic cancer of Japan Pancreas Society