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Table 1 Univariate and Multivariate analyses for recurrence-free survival

From: Downregulation of long noncoding RNA MEG3 is associated with poor prognosis and promoter hypermethylation in cervical cancer

Risk factors

Univariate analysis

Multivariate analysis

HR

P value

95% CI

HR

P value

95% CI

MEG3 expression

0.111

0.002

0.027  0.451

0.159

0.040

0.028  0.919

FIGO stage, (I, II)

3.687

<0.001

1.780  7.634

3.033

0.005

1.400  6.571

Lymph nodes metastasis (Negative, Positive)

2.095

0.043

1.023  4.291

2.259

0.048

1.007  5.070

Differentiation (Well/Moderately, Poorly)

2.134

0.040

1.036  4.396

0.670

0.406

0.201  1.722

Depth of invasion (≤2/3, >2/3)

1.358

0.403

0.663  2.783

 

HR HPV infection (Negative, Positive)

1.501

0.347

0.643  3.502

Tumor size

1.243

0.132

0.936  1.652

LVSI (Negative, Positive)

0.797

0.538

0.387  1.643

Age

0.998

0.894

0.967  1.030

Histology (Squamous, Adenocarcinoma)

0.927

0.961

0.412  2.240

Menopause (Yes, No)

1.426

0.333

0.696  2.921

  1. HR hazard ratio