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Table 1 Univariate and Multivariate analyses for recurrence-free survival

From: Downregulation of long noncoding RNA MEG3 is associated with poor prognosis and promoter hypermethylation in cervical cancer

Risk factors Univariate analysis Multivariate analysis
HR P value 95% CI HR P value 95% CI
MEG3 expression 0.111 0.002 0.027  0.451 0.159 0.040 0.028  0.919
FIGO stage, (I, II) 3.687 <0.001 1.780  7.634 3.033 0.005 1.400  6.571
Lymph nodes metastasis (Negative, Positive) 2.095 0.043 1.023  4.291 2.259 0.048 1.007  5.070
Differentiation (Well/Moderately, Poorly) 2.134 0.040 1.036  4.396 0.670 0.406 0.201  1.722
Depth of invasion (≤2/3, >2/3) 1.358 0.403 0.663  2.783  
HR HPV infection (Negative, Positive) 1.501 0.347 0.643  3.502
Tumor size 1.243 0.132 0.936  1.652
LVSI (Negative, Positive) 0.797 0.538 0.387  1.643
Age 0.998 0.894 0.967  1.030
Histology (Squamous, Adenocarcinoma) 0.927 0.961 0.412  2.240
Menopause (Yes, No) 1.426 0.333 0.696  2.921
  1. HR hazard ratio