Fig. 3

Short-term lapatinib exposure during the risk window increases mammary tumor latency in MMTV-erbB-2 transgenic mice. Mice were treated with lapatinib (100 mg/kg/day) from weeks 16-24 (8 weeks total). Mammary tumor latencies are presented with a Kaplan-Meier survival curve. The average latency for control and lapatinib groups were 37 and 42 weeks, respectively (p = 0.0154)