Fig. 7From: Blockage of glycolysis by targeting PFKFB3 suppresses tumor growth and metastasis in head and neck squamous cell carcinomaPFK15 prevents HNSCC distant metastasis in a HNSCC metastasis nude mice model. a Representative photos of the lung harvested from the mice bearing HNSCC metastasis treated with or without PFK15. b The metastatic nodules in the lung were determined by hematoxylin eosin (H & E) staining and human pan-CK immunohistochemical staining. c The quantitative of data of lung metastasis by counting the micrometastatic nodules per mice. d Kaplan-Meier survival curve of the mice treated with or without PFK15 were depicted. Mean ± S.E.M.; ***P < 0.001Back to article page