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Table 2 Univariate and multivariate analyses of different prognostic parameters in NPC patients

From: CDC42-interacting protein 4 promotes metastasis of nasopharyngeal carcinoma by mediating invadopodia formation and activating EGFR signaling

Variables Univariate analysis Multivariate analysis
HR Cl P HR Cl P
OS
 Gender 2.763 0.832–9.181 0.097
 Age 2.841 1.198–6.734 0.018 5.148 1.933–13.707 0.001
 T stage 1.317 0.554–3.129 0.533
 N stage 1.745 0.810–3.761 0.155
 M stage 9.441 3.769–23.647 <0.001 14.195 4.642–43.407 <0.001
 Clinical stage 24.271 0.134–4382.908 0.229
 CIP4 1.137 1.043–1.240 0.004 1.111 1.015–1.216 0.022
DMFS
 Gender 4.019 0.523–30.911 0.181
 Age 1.451 0.475–4.436 0.514
 T stage 0.666 0.218–2.037 0.476
 N stage 1.908 0.624–5.832 0.257
 M stage 13.355 4.058–43.955 <0.001 8.565 2.495–29.401 0.001
 Clinical stage 23.874 0.011–53961.801 0.421
 CIP4 1.199 1.046–1.374 0.009 1.159 1.006–1.336 0.041
  1. Abbreviations: OS overall survival, DMFS distant metastasis-free survival, CI confidence interval, HR hazard ratio. Statistical significance (p < 0.05) is shown in bold and italic