Fig. 2

Increased expression of survival-, migration- and angiogenesis-related genes in HUVECs after co-culture with CL1-5 cells. The mRNA expression levels of the selected genes from microarray analysis were detected by QPCR. The fold changes of survival-related genes (a), migration-related genes (b) and angiogenesis-related genes (c) in HUVECs co-cultured with CL1-5 cells were calculated relative to the HUVECs alone group and normalized to internal control TBP. The data are presented as the mean ± SD. Experiments were performed in triplicate. Gene name versus protein name: CTNNB1 vs. β–catenin; ITGAV vs. integrin alpha 3; ITGB3 vs. integrin beta 3; ACTN1 vs. α-actinin; RAC1 vs. Rac-1; PTGS2 vs. COX-2; CXCL8 vs. IL-8