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Table 2 Univariate and multivariate analysis of the association of prognosis with clinicopathologic parameters and PEG10 expression in PC

From: PEG10 overexpression induced by E2F-1 promotes cell proliferation, migration, and invasion in pancreatic cancer

Variable

Univariable analysis

Multivariable analysis

HRa (95% CIb)

P

HR (95% CI)

P

CA19-9 (≤100 vs. > 100)

1.49 (0.92–2.42)

0.107

1.15 (0.70–1.90)

0.587

Histological grade (I/I–II/II vs. II–III/III)

1.90 (1.16–3.11)

0.011*

1.96 (1.17–3.30)

0.011*

TNM (I–IIA vs. IIB–IV)

1.28 (0.81–2.03)

0.298

  

Lymph node metastasis (Absence vs. Presence)

1.17 (0.72–1.91)

0.515

  

Blood vessel invasion (Absence vs. Presence)

1.96 (1.20–3.19)

0.007*

1.90 (1.14–3.15)

0.014*

Nerve invasion (Absence vs. Presence)

1.47 (0.86–2.54)

0.162

1.25 (0.71–2.21)

0.442

PEG10 expression (Low vs. High)

1.93 (1.12–3.34)

0.018*

1.85 (1.06–3.21)

0.030*

  1. a HR hazard ratio, b CI confidence interval
  2. *p < 0.05