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Table 2 Univariate and multivariate analysis of the association of prognosis with clinicopathologic parameters and PEG10 expression in PC

From: PEG10 overexpression induced by E2F-1 promotes cell proliferation, migration, and invasion in pancreatic cancer

Variable Univariable analysis Multivariable analysis
HRa (95% CIb) P HR (95% CI) P
CA19-9 (≤100 vs. > 100) 1.49 (0.92–2.42) 0.107 1.15 (0.70–1.90) 0.587
Histological grade (I/I–II/II vs. II–III/III) 1.90 (1.16–3.11) 0.011* 1.96 (1.17–3.30) 0.011*
TNM (I–IIA vs. IIB–IV) 1.28 (0.81–2.03) 0.298   
Lymph node metastasis (Absence vs. Presence) 1.17 (0.72–1.91) 0.515   
Blood vessel invasion (Absence vs. Presence) 1.96 (1.20–3.19) 0.007* 1.90 (1.14–3.15) 0.014*
Nerve invasion (Absence vs. Presence) 1.47 (0.86–2.54) 0.162 1.25 (0.71–2.21) 0.442
PEG10 expression (Low vs. High) 1.93 (1.12–3.34) 0.018* 1.85 (1.06–3.21) 0.030*
  1. a HR hazard ratio, b CI confidence interval
  2. *p < 0.05