Journal of Experimental & Clinical Cancer Research

Table 1 Patient characteristics, whole study panel

From: Vitamin D receptor, Retinoid X receptor and peroxisome proliferator-activated receptor γ are overexpressed in BRCA1 mutated breast cancer and predict prognosis

[IRS]					BRCA1 ^mut									sporadic
		BRCA1 ^mut	sporad.		VDR			RXR			PPARγ			VDR			RXR			PPARγ
				p	<4	≥4	p	<4	≥4	p	<4	≥4	p	<4	≥4	p	<4	≥4	p	<4	≥4	p
suptype	other	8	18	ns	3	5	ns	1	7	ns	4	2	ns	11	6	ns	11	7	ns	16	2	ns
suptype	NST	30	61		4	25		11	19		12	8		40	21		30	31		55	6
G	G1-2	8	36	0.015	2	5	ns	2	6	ns	4	3	ns	30	6	0.004	17	19	ns	35	1	ns
G	G3	29	43		5	24		10	19		12	7		21	21		24	19		36	7
pT	pT1a-c	21	23	0.008	3	17	ns	4	17	ns	9	5	ns	14	9	ns	9	14	ns	19	4	ns
pT	pT2-pT4	17	56		4	13		8	9		7	5		37	18		32	24		52	4
pN	pN0	20	28	ns	2	18	ns	4	16	ns	9	5	ns	16	11	ns	14	14	ns	22	6	0.046
pN	pN+	15	47		5	10		7	8		6	4		31	16		23	24		45	2
pM	pM0	18	21	ns	4	13	ns	4	14	ns	5	6	ns	8	12	0.031	8	13	ns	18	3	ns
pM	pM+	18	49		3	15		8	10		10	4		34	15		27	22		44	5
ER	negative	27	24	0.002	6	20	ns	8	19	ns	9	9	ns	12	11	ns	15	9	ns	18	6	0.044
ER	positive	11	40		1	10		4	7		7	1		28	12		20	20		38	2
PR	negative	27	23	0.001	4	22	ns	8	19	ns	9	9	ns	14	8	ns	15	8	ns	18	5	ns
PR	positive	11	41		3	8		4	7		7	1		26	15		20	21		38	3
Her2	negative	22	25	ns	3	18	ns	5	17	ns	9	8	ns	17	7	ns	12	13	ns	22	3	ns
Her2	positive	6	19		1	5		3	3		4	1		9	10		9	10		17	2
Triple-negative	no	17	51	0.002	4	13	ns	7	10	ns	11	2	0.007	32	19	ns	25	26	ns	48	3	0.012
Triple-negative	yes	12	6		0	11		2	10		2	7		4	1		3	3		3	3
Ki67	low	10	50	ns	4	5	ns	4	6	ns	6	4	ns	32	18	ns	29	21	ns	45	5	ns
Ki67	high	10	20		2	8		4	6		6	3		13	6		9	11		17	3
age	≤41.5 y	19	16	0.002	3	15	ns	4	15	ns	4	6	ns	8	8	ns	6	10	ns	15	1	ns
age	>41.5 y	19	62		4	15		8	11		12	4		42	19		34	28		55	7

ns not significant

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ISSN: 1756-9966

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