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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: iASPP induces EMT and cisplatin resistance in human cervical cancer through miR-20a-FBXL5/BTG3 signaling

Fig. 3

miR-20a mediates iASPP-induced EMT and cisplatin resistance. a Relative miR-20a expression in CC cells and normal endometrial epithelial cell EM, as measured by qPCR analysis. b qPCR analysis of miR-20a in HeLa cells transfected with anti-miR-20a inhibitor (anti-20a) or negative control inhibitor (anti-NC), or in SiHa cells transfected with miR-20a mimic (mimic-20a) or negative control (mimic-NC). c Morphology of HeLa cells transfected with anti-20a or anti-NC. d Immunoblot of the indicated proteins in CC cells after knockdown or overexpression of miR-20a. e Representative image of invaded Hela cells in cell invasion assay. f Relative invasion of indicated CC cells after overexpression or knockdown of miR-20a. g CC cells transfected with mimic-20a or mimic-NC were treated with cisplatin, and relative cell survival was analyzed by CCK8 assays. **P < 0.01

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