Fig. 2

Exosomes derived from M2 polarized macrophages can be internalized by gastric cancer cells. a Representative transmission electron microscopy image of M2-derived exosomes (scale bar, 100 nm). b Histogram showing the particle diameter (nm) of the purified exosomes. c Exosomal markers (CD63, CD9, CD81, HSP70) were analyzed in M2 cellular protein and corresponding exosomes using western blotting (GAPDH was used as an internal reference). d The uptake of the PKH67 labelled M2-Exos was evident in MFCcells after 12 h of incubation. No stain was observed in the negative control condition. (scale bar, 10 um)