Fig. 4
From: Benserazide, a dopadecarboxylase inhibitor, suppresses tumor growth by targeting hexokinase 2
Benz inhibits glycolysis, induces apoptosis and MMP loss in SW480 cells in vitro. a-c Measurement of glucose uptake, lactate and intracellular ATP level. Metformin is used as positive control. d Cell apoptotic death analyzed by Annexin V/PI staining. e A significantly loss of MMP in SW480. All data were presented as mean ± SEM for three independent experiments. **P < 0.01 compared with the vehicle control