Table 1 Predicted pathwhays targeted by miRNAs modulated by Brivaracetam and Lacosamide
From: In vitro antineoplastic effects of brivaracetam and lacosamide on human glioma cells
KEGG pathway | p-value | #genes | #miRNAs |
|---|---|---|---|
BRIVARACETAM | |||
 Proteoglycans in cancer | 6.85E-09 | 130 | 35 |
 Fatty acid biosynthesis | 7.19E-08 | 8 | 11 |
 TGF-beta signaling pathway | 1.74E-07 | 55 | 32 |
 AMPK signaling pathway | 5.90E-07 | 84 | 36 |
 Hippo signaling pathway | 1.68E-06 | 93 | 33 |
 Glutamatergic synapse | 7.59E-06 | 72 | 35 |
 Long-term depression | 1.70E-05 | 42 | 32 |
 Adrenergic signaling in cardiomyocytes | 1.70E-05 | 92 | 37 |
 Pathways in cancer | 1.78E-05 | 219 | 38 |
 Axon guidance | 3.75E-05 | 79 | 34 |
LACOSAMIDE | |||
 Proteoglycans in cancer | 5.142E-11 | 120 | 22 |
 Fatty acid biosynthesis | 5.755E-10 | 8 | 10 |
 Hippo signaling pathway | 5.755E-10 | 92 | 24 |
 Axon guidance | 2.903E-07 | 77 | 20 |
 Long-term depression | 4.614E-07 | 43 | 21 |
 TGF-beta signaling pathway | 1.372E-06 | 49 | 20 |
 Fatty acid metabolism | 1.636E-06 | 23 | 17 |
 Adrenergic signaling in cardiomyocytes | 1.771E-06 | 86 | 24 |
 Signaling pathways regulating pluripotency of stem cells | 3.548E-06 | 82 | 22 |
 Glutamatergic synapse | 3.548E-06 | 66 | 23 |