Fig. 4

RERG suppressed ERK/NF-κB signaling pathway and expression of MMPs, IL8 and IL6 in NPC cells. Protein levels of (a) ERK/NF-κB signaling effectors and (b) MMP2 and MMP9 in RERG-transfected and empty-vector-transfected NPC cells (HK1, C666-1, HK1_EBV) were determined by western blotting (n = 3). c IL8 and IL6 in RERG-transfected and empty-vector-transfected NPC cells (HK1) were determined by western blotting (n = 3). Data are shown as means ± SD. *: P < 0.05, **: P < 0.01, ***: P < 0.001 by Student’s t-test