Fig. 5

Suppressing MYBL2 and FoxM1 expression inhibited G2/M phase transition in glioma cells. a U251 cells were transfected with indicated siRNA, and cells were collected after 48 h. Cell cycle profile was analyzed by flow cytometry. b The histogram shows the proportion of cell percentage for 48 h (upper) and 72 h (lower). c The Protein levels of cell cycle genes (P21, P27, cyclin D1, cyclin B, CDK2, and CDK6) in U251 cells were detected by Western blot.*P < 0.05