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Table 1 Treatment options for various types of bone metastatic cancers

From: Current concepts in bone metastasis, contemporary therapeutic strategies and ongoing clinical trials

  Prostate Breast Renal Lung Thyroid Multiple Myeloma
Systemic Therapy Yes Yes Yes Yes Yes Yes
Bone- Targeted Denosumab Denosumab Denosumab Consider:
Denosumab
Denosumab Pamidronate
Zoledronic Acid Zoledronic Acid Zoledronic Acid Zoledronic Acid Pamidronate Zoledronic Acid
Radium-223 Pamidronate   Zoledronic Acid  
Radiation Therapy Yes Yes Yes Yes Yes Yes
Vitamins Calcium Vitamin D Calcium Vitamin D Calcium Vitamin D Not Mentioned Not mentioned Not mentioned
Notes Possible use of Sr-89 or Sm-153     Consider embolization prior to surgical resection to reduce hemorrhage