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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2)

Fig. 1

Gambogic acid (GA) inhibited the growth of pancreatic cancer cells. Pancreatic cancer cells were treated with GA at different concentrations for 12, 24, and 48 h, respectively. Cell viability was detected using the 4,5-dimethylthiazol-2-yl)-3,5-diphenylformazan (MTT) assay, and the half maximal inhibitory concentration (IC50) was calculated. a PANC-1 cells; (b) BxPC-3 cells; (c) MIA PaCa-2 cells; (d) SW1990 cells. The IC50 of GA against these cells was calculated. Data are presented as mean ± SD (n = 5)

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