Fig. 6
From: Combination therapy of PKCζ and COX-2 inhibitors synergistically suppress melanoma metastasis
In vivo study of the combination therapy of J-4 and Celecoxib via B16-F10/C57BL mouse melanoma model. (a). Ventral and dorsal photograph of lungs removed from the mice after various treatments. (b) Comparison of lung metastatic notes in mice with various treatments. (c) The relative melanin content of lung homogenate. (d) The body weight changes of the mice during the treatment period. (e) HE staining results of livers and kidneys (100×). * P < 0.05; ** P < 0.01