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Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: Trifluoperazine, a novel autophagy inhibitor, increases radiosensitivity in glioblastoma by impairing homologous recombination

Fig. 7

TFP and radiation combination therapy significantly reduces tumor volume and prolongs survival in mice implanted with U251 and P3. a Schematic overview of the four different treatment groups in vivo. b Kaplan-Meier survival curves in nude mice bearing P3 intracranial xenograft treated with TFP, radiation or combined therapy. c Immunostaining for Ki67, γ-H2AX and Rad51 in the paraffin sections from brains from each of the four treatment groups. IP = intraperitoneally; NS = difference not significant (p > 0.05); *P < 0.05; **P < 0.01; ***P < 0.001; size bars = 50 μm

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