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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Nucleolar and spindle associated protein 1 promotes the aggressiveness of astrocytoma by activating the Hedgehog signaling pathway

Fig. 2

Association of NUSAP1 upregulation with poor survival in astrocytoma. (A and B) Kaplan-Meier overall survival and relapse-free survival curves for patients with astrocytoma (selected from LGG data of TCGA database) stratified by high and low expression of NUSAP1. c Representative images of NUSAP1 expression in astrocytoma of different grade. d Immunohistochemical analysis of astrocytoma tissue samples of different grades according to the level of NUSAP1 expression. e Statistical quantification of the average MODs of NUSAP1 staining of glioma specimens with different WHO grades. f Kaplan-Meier overall survival curves for patients with astrocytoma stratified by low (n = 69) and high (n = 152) expression of NUSAP1 (P < 0.001). *, P < 0.05)

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