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Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: The acid-sensing ion channel, ASIC2, promotes invasion and metastasis of colorectal cancer under acidosis by activating the calcineurin/NFAT1 axis

Fig. 7

High expression of ASIC2 predicts poor outcomes of CRC patients. a Immunohistochemistry analysis was performed on paraffin-embedded tissues from 147 patients with CRC using a primary antibody against ASIC2. Representative images of ASIC2 staining in adjacent tissue (left panel) and carcinoma (right panel) are shown in CRC tissues (middle panel). b IHC scores of ASIC2 in primary cancer and adjacent tissues. ASIC2 expression was significantly increased in primary cancer. c Overall survival rates of CRC patients with high or low expression of ASIC2 were estimated by Kaplan-Meier analysis

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