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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: High expression of Bruton’s tyrosine kinase (BTK) is required for EGFR-induced NF-κB activation and predicts poor prognosis in human glioma

Fig. 3

Ibrutinib inhibits the migration and invasion of glioma cells. (a-d) Ibrutinib reduced the migration ability of U87 and U251 cells as examined by wound healing assay. (e-h) Ibrutinib reduced the invasion ability of U87 and U251 cells as examined by transwell assay. The positive numbers of cells were counted and normalized to the control group. The data are expressed as the mean ± SEM from three independent experiments

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