Fig. 2From: Elevated expression of Par3 promotes prostate cancer metastasis by forming a Par3/aPKC/KIBRA complex and inactivating the hippo pathwayPar3 knockdown inhibits while Par3 overexpression facilitates PC3 cell migration and invasion in vitro. a Stable knockdown of Par3 inhibits both migration and invasion in PC3 cells by transwell assays. Migratory and invasive cells are counted and averaged from five randomly selected fields respectively. Scale Bar: 20 μm b Overexpression of Par3 activates both migration and invasion in PC3 cells by transwell assays. Migratory and invasive cells are counted and averaged from five randomly selected fields respectively. Scale Bar: 20 μm. All data are represented as mean ± SD from triplicate experiments. *: p < 0.05, **: p < 0.01Back to article page