Journal of Experimental & Clinical Cancer Research

Table 2 Concordance between ISH and MLPA in the internal and external validation set

From: Breast carcinomas with low amplified/equivocal HER2 by Ish: potential supporting role of multiplex ligation-dependent probe amplification

	DDISH (N = 170)*		Cohen’s K Statistic [95% CI]
	NA	A
	94	76
MLPA			0.548 [0.419–0.677]
NA	86	29
A	8	47
	FISH (N = 108)**
	NA	A
	87	21
MLPA			0.464 [0.280–0.648]
NA	64	2
A	23	19

NA Non Amplified, A Amplified, MLPA A = Amplified + Gain
* Internal set ** External set

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ISSN: 1756-9966

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