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Table 2 Concordance between ISH and MLPA in the internal and external validation set

From: Breast carcinomas with low amplified/equivocal HER2 by Ish: potential supporting role of multiplex ligation-dependent probe amplification

  DDISH (N = 170)* Cohen’s K Statistic [95% CI]
  NA A  
  94 76  
MLPA    0.548 [0.419–0.677]
 NA 86 29  
 A 8 47  
  FISH (N = 108)**  
  NA A  
  87 21  
MLPA    0.464 [0.280–0.648]
 NA 64 2  
 A 23 19  
  1. NA Non Amplified, A Amplified, MLPA A = Amplified + Gain
  2. * Internal set ** External set