Fig. 5
From: Hypermethylation and loss of retinoic acid receptor responder 1 expression in human choriocarcinoma
RARRES1 expression in placental tissue and Swan71 cells. a RARRES1 localization in syncytial knots and apoptotic cells was analyzed by immunohistochemistry of placental sections (a and b) and immunofluorescence of fixed Swan71 cells (c and d). RARRES1 positivity is indicated by brown (a and b) or red (c) staining. Nuclei are blue (a-d). b RARRES1 expression in dividing cells was analyzed by immunohistochemistry (a and b) of placental sections and immunofluorescence staining of Swan71 cells (c-h). Black arrow heads mark a VT during mitosis (b). Swan71 cells showed strong RARRES1 positivity during meta- (c and d), ana- (e and f) and telophase (g and h) of mitosis. The bars equal 100 μm