Fig. 5
From: MicroRNA-150 enhances radiosensitivity by inhibiting the AKT pathway in NK/T cell lymphoma
The PI3K tyrosine kinase inhibitor LY294002 synergistic effect of miR-150. a The NKTL cells lines NK-92 and Hank-1 were transfected with miR-150 or miR-control. The cells were then treated with or without LY294002 for 1 h before exposure to different doses radiation. Survival fractions were calculated and analyzed (Kruskal-Wallis test); b Western blot analysis of p-mTOR and p-Akt levels in NK-92 and Hank-1 cells transfected with miR-150 or miR-control, then treated with LY294002 for 1 h, and finally exposed to a 6 Gy dose of radiation for another 24 h. #P < 0.05, *P < 0.01