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Table 5 Performance characteristics of the 44-gene expression signature in two test sets

From: Identification and validation of a 44-gene expression signature for the classification of renal cell carcinomas

  Test Set 1 Test Set 2
  n Sensitivity Specificity n Sensitivity Specificity
Normal 129 94.6% 100.0% 8 100.0% 98.3%
ccRCC 534 94.2% 95.7% 26 96.2% 96.1%
chRCC 66 90.9% 97.8% 40 92.5% 97.8%
pRCC 291 92.1% 97.8% 28 89.3% 99.0%
Oncocytoma / / / 27 92.6% 98.2%
Total 1020 Overall accuracy = 93.4% 129 Overall accuracy = 93.0%