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Table 5 Performance characteristics of the 44-gene expression signature in two test sets

From: Identification and validation of a 44-gene expression signature for the classification of renal cell carcinomas

 

Test Set 1

Test Set 2

 

n

Sensitivity

Specificity

n

Sensitivity

Specificity

Normal

129

94.6%

100.0%

8

100.0%

98.3%

ccRCC

534

94.2%

95.7%

26

96.2%

96.1%

chRCC

66

90.9%

97.8%

40

92.5%

97.8%

pRCC

291

92.1%

97.8%

28

89.3%

99.0%

Oncocytoma

/

/

/

27

92.6%

98.2%

Total

1020

Overall accuracy = 93.4%

129

Overall accuracy = 93.0%