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Table 2 Univariate analysis of factors associated with survival and recurrence

From: MCM6 promotes metastasis of hepatocellular carcinoma via MEK/ERK pathway and serves as a novel serum biomarker for early recurrence

Variables

OS

TTR

Hazard ratio (95% CI)

P value

Hazard ratio (95% CI)

P value

Age (years)

0.632 (0.349–1.142)

0.128

0.722 (0.425–1.229)

0.231

AFP (μg/l)

0.335 (0.141–0.796)

0.013

0.529 (0.272–1.028)

0.060

HBsAg

2.451 (0.758–7.925)

0.134

2.227 (0.802–6.186)

0.124

GGT (U/I)

1.991 (1.056–3.754)

0.033

1.869 (1.067–3.274)

0.029

Child-Pugh score

1.437 (0.347–5.940)

0.617

1.160 (0.282–4.769)

0.837

Tumor capsule

0.902 (0.381–2.132)

0.814

1.266 (0.542–2.956)

0.586

Tumor differentiation

1.778 (0.633–4.994)

0.275

1.415 (0.510–3.926)

0.505

Vascular invasion

2.433 (1.015–5.833)

0.043

2.563 (1.141–5.760)

0.023

Liver-cirrhosis

1.357 (0.915–3.112)

0.048

1.845 (1.055–3.228)

0.028

Tumor size (cm)

1.893 (1.322–3.473)

0.039

1.856 (1.077–3.199)

0.026

Tumor number

1.438 (0.812–2.203)

0.210

1.256 (0.860–1.903)

0.392

Early recurrence

1.047 (0.418–2.525)

0.005

1.709 (0.583–1.859)

0.023

MCM6 expression

2.001 (1.043–2.187)

0.021

1.819 (1.292–2.561)

0.021

  1. (P < 0.05) had been marked in boldface