Fig. 1

EPS8 expression in AML patients. a Box plot presenting the median level of EPS8 expression in 501 AML patients at diagnosis and in 72 healthy volunteers from GSE13159 dataset. b Kaplan-Meier estimated curves represent the percentage of overall survival of AML patients from GSE12417 dataset. High EPS8 expression was associated with poor overall survival (median survival, 330 vs 624 days). c Kaplan-Meier estimated curves represent the percentage of overall survival of AML patients from TCGA database. High EPS8 expression was associated with poor overall survival (median survival, 424 vs 792 days). d Changes in important EGF/PDGF signaling pathway targets after EPS8 knockdown analyzed with an RT²profiler™ PCR assay in KG1α cells