Fig. 8
Synergistic effect of CP-EPS8-NLS with chemotherapeutic agents in a KG1α xenograft model. a KG1α cells (1 × 107 per flank) were injected into the right flank of mice. When the volume of tumors reached 100 mm3, the mice were randomly divided into five groups (5 mice in each group). Then, CP-EPS8-NLS, DNR or CP-EPS8-NLS combined with DNR were intraperitoneally injected into the mice every other day. Mice injected with mutated CP-EPS8-NLS or PBS were used as controls. b The volume of each tumor was measured every 3 days for 15 days. c Body weight of the mice. d The volume of each tumor was measured after extraction from mice at the experimental endpoint. e Image of tumors excised from mice after 15 days of treatment